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Wednesday, July 22, 2020 | History

6 edition of Gap junctions found in the catalog.

Gap junctions

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Published by Cold Spring Harbor Laboratory in Cold Spring Harbor, N.Y .
Written in English

    Subjects:
  • Gap junctions (Cell biology) -- Congresses

  • Edition Notes

    Statementedited by Michael V.L. Bennett, David C. Spray.
    ContributionsBennett, Michael V. L. 1931-, Spray, David C., Cold Spring Harbor Laboratory.
    Classifications
    LC ClassificationsQH603.C4 G36 1985
    The Physical Object
    Paginationxiii, 409 p. :
    Number of Pages409
    ID Numbers
    Open LibraryOL2530729M
    ISBN 100879691875
    LC Control Number85011329

      Gap junctions between glial cells or neurons are ubiquitously expressed in the mammalian brain and play a role in brain development including cell differentiation, cell migration and survival, and tissue homeostasis, as well as in human diseases including hearing loss, neuropathies, epilepsy, brain trauma, and cardiovascular : Elsevier Science. Presenting state-of-the-art protocols to study gap junctions, this detailed book first focuses on the use of methods and tools to investigate the different aspects of connexin expression and gap.

    Gap junctions allow various molecules and ions to pass freely between cells. A gap junction channel is composed of two connexons, also known as hemichannels that line up across the intercellular space. Most gap junction hemichannels are composed of a complex of six connexin proteins, each characterized by four transmembrane domains. Dorsal root ganglion (DRG) or spinal ganglia are present in relation to the dorsal ramus of the spinal nerves. The neurons in the dorsal root ganglion are pseudounipolar in type. The single process from the soma or body will divide into the central and peripheral processes. Dorsal root ganglion neurons constitute the first-order neurons for the pain pathways and can be categorized as small Author: Vishwajit Ravindra Deshmukh.

      This long-awaited, first comprehensive book on this topic of fundamental importance in our understanding of cancer begins with an overview of cellular junctions, before covering cell-matrix junctions, cell-cell junctions and cell-matrix and cell-cell adhesion in separate sections. Gap junctions are intercellular channels established between cells through which small molecules can pass. Within the spinal cord, the majority of gap junctions are found between astrocytes. Gap junctions allow for fast communication between cells over long distances.


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Gap junctions Download PDF EPUB FB2

This volume provides neuroscience researchers and students with a single source for information covering the physiological, behavioral and pathophysiological roles of gap junctions in the brain. In addition, the book also discusses human disease conditions associated with mutations in single gap junction connexion genes, making it applicable to clinicians doing translational : Hardcover.

Gap junctions are present in nearly all tissues, regardless of their embronic origin and have long been of great interest to scientists from many different disciplines. The international meeting on which this book is based brought together scientists from Book Edition: 1. Communication between cells via intercellular channels – gap junctions – appears essential to certain developmental processes and appropriate organ function.

Gap Junctions in Development and Disease aims to describe the molecular events underlying impaired development and disease. Beginning with a comprehensive review of various mouse and human genes encoding the Format: Hardcover.

Gap junctions are present in nearly all tissues, regardless of their embronic origin and have long been of great interest to scientists from many different disciplines. The international meeting on which this book is based brought together scientists from 12 countries and almost as many scientific disciplines.

The NOOK Book (eBook) of the Gap Junctions in the Brain: Physiological and Pathological Roles by Ekrem Dere at Barnes & Noble.

FREE Shipping on $35 or Due to COVID, orders may be delayed. Gap junctions book you for your : Ekrem Dere. Description. Gap junctions between glial cells or neurons are ubiquitously expressed in the mammalian brain and play a role in brain development including cell differentiation, cell migration and survival, and tissue homeostasis, as well as in human diseases including hearing loss, neuropathies, epilepsy, brain trauma, and cardiovascular disease.

Book Description Gap junction channels are a group of intercellular channels expressed in tissues and organs to synchronize many physiological processes.

A gap junction channel is formed by the docking of two hemichannels, and each hemichannel is a hexamer of connexins. Gap junctions provide one of the most common forms of intercellular communication. The structures underlying these communicating cell junctions 1 were soon resolved in membrane associated particles forming aggregates of six subunits.

2 They are composed of membrane proteins that form a channel that is permeable to ions and small molecules, connecting the cytoplasm of acdjacent by: 1. Gap junctions are communicating junctions composed of clusters of connexons that allow molecules smaller than about daltons to pass directly from the inside of one cell to the inside of the next.

Cells connected by gap junctions share many of their inorganic ions and other small molecules and are therefore chemically and electrically coupled. Purchase Gap Junctions, Volume 30 - 1st Edition. Print Book & E-Book. ISBNBook Edition: 1. Order Gap Junctions ISBN @ € Qty: This monograph contains research articles from the leading laboratories around the world on gap junctions, the intercellular channels that allow communication between neighbouring cells.

Gap Junctions. Gap junctions in animal cells are like plasmodesmata in plant cells in that they are channels between adjacent cells that allow for the transport of ions, nutrients, and other substances that enable cells to communicate (Figure \(\PageIndex{5}\)).

Structurally, however, gap junctions and plasmodesmata differ. Gap junctions allow the exchange of ions, second messengers, and small metabolites between adjacent cells and are formed by two unrelated protein families, the pannexins and connexins.

Presenting state-of-the-art protocols to study gap junctions, this detailed book first focuses on the use of methods and tools to investigate the different aspects of connexin expression and gap junction regulation. The second part of the volume describes several methods to probe gap junction.

Summary This chapter contains sections titled: Definition Historical Perspective Molecular Composition of the Gap Junction Domain Gap Junction Growth, Internalization, and Renewal Significance of t. Gap junctions between glial cells or neurons are ubiquitously expressed in the mammalian brain and play a role in brain development including cell differentiation, cell migration and survival, and tissue homeostasis, as well as in human diseases including hearing loss, neuropathies, epilepsy, brain trauma, and cardiovascular : Ekrem Dere.

Gap Junctions - Exam 3. STUDY. PLAY. gap junction. used to establish function of electrical synapses. unc-7 and unc-9 are gap junction genes.

deletions leads to kinks and inability to move. glia. contain the large majority of connexins in the brain. cx COVID Resources. Reliable information about the coronavirus (COVID) is available from the World Health Organization (current situation, international travel).Numerous and frequently-updated resource results are available from this ’s WebJunction has pulled together information and resources to assist library staff as they consider how to handle coronavirus.

Gap junctions: structure and function (Review) W. Howard Evans* and Patricia E. Martin Departments of Medical Biochemistry & Diagnostic Radiology, University of Wales College of Medicine, Heath Park, Cardiff CF14 4XN, Wales, UK Summary Gap junctions are plasma membrane spatial microdomains constructed of assemblies of channel proteins called.

Gap junctions, also called nexus, communicating junctions, or Gap junctions are widespread in epithelial tissues throughout They differ from the occluding and anchor- ing junctions, in t.

The main objective of Gap Junctions in Development and Disease is to describe the molecular events that cause impairments in development and disease. Communication between cells via intercellular channels, so called gap junctions, appears to be essential for certain developmental processes and appropriate organ function.Gap Junctions in Development and Disease aims to describe the molecular events underlying impaired development and disease.

Beginning with a comprehensive review of various mouse and human genes encoding the channel-forming connexins, later chapters describe several connexin mutations associated with human diseases such as hereditary deafness and female infertility.The gap junction pore size varies depending on the type of connexins, but generally, the molecules under 1 kDa are able to pass through while larger ones can not.

Therefore, cells connected by gap junctions are electrically connected (ions can freely pass), they can share cellular energy (ATP), and second messenger signaling molecules like Ca 2.