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Wednesday, July 22, 2020 | History

2 edition of Studies on the metabolism of plant sterols in the rat. found in the catalog.

Studies on the metabolism of plant sterols in the rat.

Mandepanda Thimmiah Subbiah

Studies on the metabolism of plant sterols in the rat.

by Mandepanda Thimmiah Subbiah

  • 274 Want to read
  • 1 Currently reading

Published in Toronto .
Written in English

    Subjects:
  • Cholesterol -- Metabolism,
  • Rats,
  • Sterols

  • Edition Notes

    ContributionsToronto, Ont. University.
    The Physical Object
    Paginationx, 161 leaves.
    Number of Pages161
    ID Numbers
    Open LibraryOL20793819M

    Title:Molecular Insights into the Mechanisms Underlying the Cholesterol- Lowering Effects of Phytosterols VOLUME: 26 ISSUE: 37 Author(s):Lídia Cedó, Marta Farràs, Miriam Lee-Rueckert and Joan Carles Escolà-Gil* Affiliation:Institut d'Investigacions Biomediques (IIB) Sant Pau, Barcelona, Integrative Systems Medicine and Digestive Disease Division, Department of Surgery and Cancer, Imperial Cited by: 1. Two groups of young litter mate rats were fed on diets consisting of a mixture of soya bean meal, corn oil, agar, starch, salt mixture and vitamin supplements, prepared so that one group received 11 and the other 34 per cent, fat, the protein intake being practically the same for both groups. Most of the animals on the high fat diet had a higher percentage of liver sterols than those on the low Author: H. C. Eckstein.

    Studies have shown that oral administration of plant sterols combined with plant enzymes is able to balance TH1 and TH2 cell types. Clinical Uses of Plant Sterols. Numerous studies have now emerged showing that plant oils in the form of sterols and sterolins have profound health benefits. In biology and biochemistry, a lipid is a macrobiomolecule that is soluble in nonpolar solvents. Non-polar solvents are typically hydrocarbons used to dissolve other naturally occurring hydrocarbon lipid molecules that do not (or do not easily) dissolve in water, including fatty acids, waxes, sterols, fat-soluble vitamins (such as vitamins A, D, E, and K), monoglycerides, diglycerides.

    Phytosterols. The new breed of wonderchemicals? Phytosterols are natural plant estrogens. Because of their reputations in folk lore as abortifacients, menstrual cycle disruptors and ecbolic (hastening labour or miscarriage) agents and are known to stimulate uterine tissue and have hormonal influences on the reproductive tract, the World Health Organisation sponsored a huge study to investigate. ISBN: OCLC Number: Notes: "The proceedings of the EUROFOODCHEM XI meeting entitled Biologically-active Phytochemicals in Food: Analysis, Metabolism, Bioavailability and Function held at the Norwich Research Park, Norwich, UK on September "--Title page verso.


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Studies on the metabolism of plant sterols in the rat by Mandepanda Thimmiah Subbiah Download PDF EPUB FB2

STEROL METABOLISM. Previous studies performed with a tobacco mutant sterov overproducing sterols have shown that the free sterol content of this mutant remained close to this of wild-type plants and that the excess of sterols was converted into steryl esters (mostly steryl palmitate, oleate, linoleate and linolenate) which accumulated in lipid.

Sterols occur in the membranes of plants, animals, and microorganisms and are termed phytosterols, zoosterols, and mycosterols, respectively.

Cholesterol is the main zoosterol, but sterols in plants commonly occur as mixtures with β-sitosterol, campesterol, and stigmasterol representing three of the major sterols are all Δ 5-sterols (Figure 6), but Δ 7-sterols may also be.

In book: Biochemical Aspects of Human Nutrition, Chapter: Plant sterols, cholesterol metabolism and related disorders, Publisher: Transworld Research Network, Editors: Luciana Avigliano and Luisa. Studies in the general population have shown that 2 to 3 g of plant sterols per day lowers low-density lipoprotein cholesterol by 6% to 15% in hypercholesterolemic children and adults.

73 There is no contraindication to the use of commercial products containing plant sterols (e.g., Benecol or Take Control margarines) in patients with CKD. Foods with plant stanol or sterol esters lower serum cholesterol levels.

We summarize the deliberations of 32 experts on the efficacy and safety of sterols and stanols. Food enriched with plant sterols and plant stanols. Clinical trials that demonstrated a cholesterol-lowering effect have primarily used plant sterol or stanol esters solubilized in fat-containing foods, such as margarine or onal studies indicate that low-fat or even nonfat foods can effectively deliver plant sterols or stanols if they are adequately solubilized (37, 66).

REFERENCES. MacLatchy et al, “The Phyto-Estrogen B-Sitosterol Alters the Reproductive Endocrine Status of Goldfish,” Toxicology & Applied Pharmocology Mellanen et al, “Wood-Derived Estrogens: Studies in Vitro with Breast Cancer Cell-lines, and in Vivo in Trout,” Toxicology and Applied Pharmocology Howell et al, “Gonopodial.

In a clinical trial to examine the effects of plant sterols and plant stanols-enriched margarine on plasma lipid and phytosterol concentrations, de novo cholesterol synthesis and absorption rates in the context of a controlled diet, fifteen hypercholesterolemic men were fed either a diet of prepared foods alone or a diet containing g plant.

The primary sterol found in animal organisms is cholesterol. Analogs of cholesterol in the plant kingdom are, as a class, termed phytosterols. Plant sterols resemble cholesterol structurally in that they all have a steroid nucleus, a 3β hydroxyl group, and a double bond between carbon atoms 5 and 6.

To explore mechanisms in plant sterol homeostasis, we have here increased the turnover of sterols in Arabidopsis (Arabidopsis thaliana) and potato (Solanum tuberosum) plants by overexpressing four mouse cDNA encoding cholesterol hydroxylases (CHs), hydroxylating cholesterol at the C-7, C, C, or C positions.

Compared to the wild type, the four types of Arabidopsis Cited by: It is considered that through plant sterols, Maca stimulates endocrine system helping to maintain hormonal balance in a way that is not yet well understood (2, 18). According to Muller (6), these sterols are used by the body with the help of the pituitary to improve adrenal function, ovarian and testicular function, as well as the functioning Cited by: 6.

METABOLISM OF PLANT TERPENOIDS GEORGE R. WALLER Department of Biochemistry, Agricultural Experimental Station, Oklahoma State University, Stillwater, OklahomaU.S.A. INTRODUCTION THE number of terpenoids that are synthesized by plants is probably larger than any other group of naturally occurring compounds.

Borgstrom B. Quantitative aspects of the intestinal absorption and metabolism of cholesterol and ß-sitosterol in the rat. J Lipid Res ; 8. Swell L, Boiter TA, Field H, Treadwell CR. The absorption of plant sterols and their effect on serum and liver sterol levels. J Nutr ; 9.

Serum noncholesterol sterols indicate overall cholesterol metabolism in a variety of experimental and clinical conditions. In patients with advanced primary biliary cirrhosis serum cholestanol, a 5ä‐derivative of cholesterol, is markedly increased, and cholesterol precursors, which are indicators of cholesterol synthesis, are clearly reduced, as is the ratio of plant sterols (campesterol.

Brassinosteroids (BRs) are endogenous plant hormones essential for the proper regulation of multiple physiological processes required for normal plant growth and development. Since their discovery more than 30 years ago, extensive research on the mechanisms of BR action using biochemistry, mutant studies, proteomics and genome-wide transcriptome analyses, has helped refine.

Studies such as by Torres-Sanchez have found an inverse correlation between consumption of phytochemicals and risk of breast cancer among postmenopausal women suggesting a potential role for plant sterols in mitigating risk. Plant sterols may be one such nutritional component which may likewise play a role in attenuating breast cancer risk or Cited by: Mandepanda Thimmiah Subbiah has written: 'Studies on the metabolism of plant sterols in the rat' -- subject(s): Sterols, Rats, Metabolism, Cholesterol Asked in Botany or Plant Biology, Genetics.

Mandepanda Thimmiah Subbiah has written: 'Studies on the metabolism of plant sterols in the rat' -- subject(s): Sterols, Rats, Metabolism, Cholesterol Asked in Biology, Nutrition, Genetics.

The pathogenesis of colorectal cancer is currently unknown. Epidemiological studies in man and studies in experimental animals have implicated various classes of compounds as potential tumor promoters or tumor inhibitors.

Plant sterols, a group of compounds found in vegetables, will be the focus of this by: Unfortunately, this book can't be printed from the OpenBook.

If you need to print pages from this book, we recommend downloading it as a PDF. Visit to get more information about this book, to buy it in print, or to download it as a free PDF.

The major function of vitamin D in vertebrates is maintenance of calcium homeostasis, but vitamin D insufficiency has also been linked to an increased risk of hypertension, autoimmune diseases, diabetes, and cancer.

Therefore, there is a growing awareness about vitamin D as a requirement for optimal health. Vitamin D3 is synthesized in the skin by a photochemical conversion of Cited by: In this study, we evaluated the effects of dietary plant sterols and stanols as their fatty acid esters on the development of experimental colitis.

The effects were studied both in high- and low-fat diet conditions in two models, one acute and another chronic model of experimental colitis that resembles gene expression in human inflammatory bowel disease (IBD).Cited by: Stigmastanol (sitostanol) is a phytosterol found in a variety of plant sources.

Similar to sterol esters and stanol esters, stigmastanol inhibits the absorption of cholesterol from the diet. Animal studies suggest that it also inhibits biosynthesis of cholesterol in the liver. [verification needed]Stigmastanol is the product of the reduction of β-sitosterol and the hydrogenation of Number: